Confocal image of a spheroid containing SpheroSeev fibers (green) with cells (blue).
Confocal image of a stained SpheroSeev fibers.
I have used “Spheroseev” fibers to make HT1080 cancer cells spheroids, and it worked really well. I could find homogenous size distribution, and most of the spheroids are viable. I recommend using this product.
Alakesh Das, PhD
Irit Sagi Lab
Dept of Biological Regulation
Weizmann Institude of Science
We used Spheroseev product in order to grow epithelial ovarian cancer (EOC) spheroids from human ovarian cancer cell line – Ovcar3. In the presence of the Spheroseev, the viability of the spheroid increased significantly. In addition, the product improved the sensitivity of the cytotoxicity assay (using chemotherapy and Ovcar3 spheroids). Therefore, I would like to recommend the use of this product in a routine growth of EOC spheroids.
Dr Dalit Landesman-Milo PhD
Lab manager, Prof Peer laboratory for Precision Nanomedicine,
I used “SpheroSeev” for primary glioblastoma cell culture. It helps to form nice and stable tumorspheres, which I never achieved before. With other kinds of matrix, my GBM cell always tends to differentiate, but “SpheroSeev” keeps the stemness of the cells. Great product!
Ph.D. Student, Oren Ram Lab
Human normal primary spheroids production using “SpheroSeev”, dramatically increased viability.
Orit Harari-Steinberg, Ph.D, Senior
Researcher & Lab Manager
Regenerative Medicine Research Lab
Pediatric Stem Cell Research Institute
Sheba Medical Center
“SpheroSeev” 3D matrix really works well. I could find a nice spheroid. Product was used with colorectal cancer cell lines. I had used different matrixes previously from different companies but I should say from my experience that “SpheroSeev” works better than regular spheroid matrix. I like it!
Lab of Prof. Yosef Yarden
Dept. of Biological Regulation
Weizmann Institute of Science
SpheroSeev combines the advantages of scaffold-based and scaffold-free technologies.
SpheroSeev fibers’ nano and micro dimensions are similar to the natural ECM, providing a tissue-like environment for cells.
SpheroSeev fibers have high porosity, enabling better access to oxygen and nutrients, thereby supporting prolonged viability and functionality.
SpheroSeev fibers have extra strength and elasticity, providing mechanical cushioning and protection to individual cells within the organoid.
SpheroSeev fibers’ nano and micro dimensions are similar to the natural ECM, providing a tissue-like environment for cells
Adipose-derived mesenchymal stem cells (MSCs) cultured as spheroid with SpheroSeev demonstrate tissue-like spread morphology and higher viability than spheroid without SpheroSeev. [Green – viable cells, Red – dead cells]
L929 cell line cultured as spheroid with SpheroSeev demonstrates delayed necrotic core formation and higher viability.
[Stained with PI and CalceinAM] [Green – viable cells, Red – dead cells]
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Add the protein fiber to an existing experiment (a 5-minute protocol)
Discover the benefits of SpheroSeev: within days your organoid will be bigger and more vital and will survive longer
In order to make the decision of trying SpheroSeev in your own lab experiments and find it effective to your research, we have created a sample that you can try with almost no effort or meaningful costs.
The sample of [specs] costs only 300$(to be decided – less than 300$).
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Based on over a decade of academic research performed at the Hebrew University, Seevix was founded in 2014 to revolutionize material science by using spider silk’s unique natural properties to create high-performance products and materials.
We are passionate about science. We employ a remarkable multidisciplinary R&D team of biologists, chemists and engineers to ensure we remain a cut above the rest.
Our Address: Minrav Building, Biotechnology Park Hadassah Ein Kerem Campus Jerusalem, Israel 9112001